You can use the AnimationState API (higher level) or the Timeline API (lower level):
Applying Animations - Spine Runtimes Guide
Eg:
state.setAnimation(0, "walk", true);
TrackEntry run = state.setAnimation(1, "run", true);
run.alpha = 0.5f
See TrackEntry alpha
. You can adjust alpha between 0 (all walk) and 1 (all run). Between 0 and 1 is a mix of the two. You can easily experiment with this using Preview in the editor:
Preview - Spine User Guide