yugutou I have checked your Spine project and confirmed that I can reproduce the problem. I guess it is affected by the following items that were fixed in 4.2.60-beta:

Don't wrap rotation and shear Y for a transform constraint when local is checked and relative is not.

The problem is caused by a transform constraint named body_1, which has just been configured with a Rotation offset of 180, Local checked and Relative unchecked, so I think this might be the case. In fact, I was able to reproduce this problem in 4.2.00, so I don't think this is a bug caused by a fix made in a recent patch version, but rather a result of fixing an issue that existed for a long time.

This problem can be fixed by setting the rotation offset from 180 to -180:

We apologize for the inconvenience of having to manually fix this, but it should be a very rare occurrence.

yugutou As I mentioned in my earlier answer, this behavior is the result of fixing a problem that has been around for a long time, so there are probably no more fixes for it. It might be possible to add something to automatically fix the transform constraint if it exists, which is the case here, but since this is a fairly rare case, I think it would be faster to fix it manually. Or are you seeing a lot of the same issues in other projects? If so, we might consider something that can be fixed automatically.