What version of Windows are you using?
Are you using any downloaded window-management or graphics-related programs that would override things in Windows?
Do you have a particularly old computer, have a small amount of RAM, or use unusual graphics hardware?
Also remember.
Spine 3.6 has an auto-save/auto-backup feature. The default setting saves your project every 15 mintes. But remember to save often anyway.
And note that Spine saves backups of previous manually-saved versions of your project in your Spine folder in case something does wrong like power loss or a crash.